Adenocarcinoma of the Appendix
Grading / Staging / Report
- Grading differs somewhat compared to colorectal adenocarcinoma
- Non-mucinous carcinomas are graded as are colorectal adenocarcinoma NOS
- Low grade
- 50-100% gland formation
- High grade
- 0-49% gland formation
- Low grade
- Mucinous carcinomas are definitionally high grade in the appendix
- Virtually all are microsatellite stable, unlike in the colorectum
- Signet ring carcinomas are definitionally high grade
- Non-mucinous carcinomas are graded as are colorectal adenocarcinoma NOS
- Staging: TNM from AJCC, similar to colorectal
