Surgical Pathology Criteria

Dysplasia of the Anus

Grading / Staging / Report

Grading

Low grade squamous intra-epithelial lesion (LSIL) High grade squamous intra-epithelial lesion (HSIL)
Low nucleus/cytoplasmic (NC) ratio NC ratio ≥ 1
Orderly maturation Disorderly maturation
Atypical cells confined to superficial layer Atypical cells at all layers
Mitotic figures confined to basal layers unless inflamed Mitotic figures at all levels
No atypical mitotic figures Atypical mitotic figures may be seen

Staging

Report

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