Sloughing Esophagitis
Differential Diagnosis
- Cutaneous bullous disorders should be ruled out
- Immunofluorescence is negative for C3 and Ig
- Eosinophilic esophagitis may slough the superficial layer of mucosa with an eosinophilic infiltrate
- Large numbers of eosinophils are not seen in sloughing esophagitis
- Artifactually induced fragments of mucosa will not generally show features such as:
- Epithelial necrosis
- Bacterial and fungal colonies
- Keratosis
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