Surgical Pathology Criteria

Food Enteropathy

Differential Diagnosis

 

Food Protein Enteropathy Autoimmune Enteropathy
Predominantly eosinophilic infiltrate Predominantly T cell infiltrate
Frequent associated allergy or atopy No association with other allergies or atopy
Resolved by elimination of offending food from diet Not related to diet
For pediatric autoimmune enteropathy with associated polyendocrinopathy see IPEX syndrome.

 

Food Protein Enteropathy Common Variable Immunodeficiency – GI Involvement
Numerous plasma cells Plasma cells frequently markedly decreased
Predominantly eosinophilic infiltrate Nodular lymphoid hyperplasia
Frequent associated allergy or atopy No association with other allergies or atopy
Resolved by elimination of offending food from diet Not related to diet

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