Surgical Pathology Criteria

Eosinophilic Proctocolitis

Differential Diagnosis

Eosinophilic GI disorders by location

Eosinophilic Esophagitis Eosinophilic Gastroenteritis Eosinophilic Proctocolitis
Confined to esophagus Involves stomach and/or small intestine Confined to rectum and colon
Good response to dietary manipulation Poor response to dietary manipulation Good response to dietary manipulation

Eosinophilic (Allergic) Proctocolitis Ulcerative Colitis
May occur <12 months of age Very rare <12 months
Marked tissue eosinophilia >60/10 HPF May have moderate numbers of eosinophils

Eosinophils may be numerous in other diseases:

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