Crohn Disease
Clinical
- The risk of carcinoma is elevated in both ulcerative colitis and Crohn disease
- A diagnosis of high grade dysplasia frequently leads to colectomy
- A diagnosis of low grade dysplasia may result in a variety of clinical responses
- Some merely increase the frequency of follow up screening
- Some recommend colectomy, especially if the dysplasia is identified in multiple sites or on subsequent endoscopy
- A diagnosis of indefinite for dysplasia typically leads to medical therapy and rebiopsy after inflammation is reduced
- A diagnosis of no dysplasia usually results in routine follow up endoscopy in 3 to 5 years
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