Collagenous Gastritis
Differential Diagnosis
- Radiation
- Diffuse fibrosis rather than just below basement membrane
- Scleroderma
- Fibrosis also around crypts and may be diffuse
- Artifact of sectioning
Tangential Sectioning Collagenous Gastritis Present only where adjacent glands cut as cross-sections Present even when adjacent glands are cut longitudinally Indistinct edges but no entrapped elements Jagged edges with entrapped capillaries and inflammatory cells Lacks chronic inflammatory infiltrate Prominent chronic inflammatory infiltrate in lamina propria
