Surgical Pathology Criteria

High Grade Neuroendocrine Carcinoma (Small Cell Carcinoma) of the Breast

Supplemental Studies

Immunohistology

Keratin
10/10
CK7
8/10
CK20
0/10
Neuron specific enolase
17/19
Synaptophysin
8/15
Chromogranin A
6/16
Calcitonin
3/12
Gastrin releasing peptide
5/13
E-cadherin
11/11
TTF1
2/10
ER
6/12
PR
9/11
Her2neu
0/10
Modified from Shin 2000

Prognostic/Therapeutic Markers

Genetic analysis

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