Pubertal Macromastia
Differential Diagnosis
| Pubertal Macromastia | Juvenile Fibroadenoma |
|---|---|
| Diffuse, not circumscribed | Circumscribed |
| Fibrous or fatty stroma | Cellular stroma |
| Rare | More common as a cause of adolescent breast enlargement |
| Pubertal Macromastia | Phyllodes Tumor |
|---|---|
| Young age (10-17 years) | Almost all over 30 years |
| No discrete mass | Mass usually present |
| No broad papillae | Broad papillae inserted into spaces |
| Paucicellular stroma | Cellular stroma |
| No stromal mitotic figures | May have stromal mitotic activity |
| No stromal atypia | Stromal atypia may be present |
| Pubertal Macromastia | Juvenile Papillomatosis |
|---|---|
| Diffuse | Circumscribed |
| Massive enlargement | Mean size 4 cm |
| Usually bilateral | Usually solitary |
| Predominantly stromal process | Prominent cysts |

