Phyllodes Tumor of the Breast
Definition
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Mixed epithelial and stromal/mesenchymal proliferation of breast characterized by increased stromal cellularity and characteristic broad "leaf-like" papillae inserted into cleft-like spaces
Alternate/Historical Names
Diagnostic Criteria
- Usually large and grossly circumscribed
- Fibroepithelial proliferation with broad "leaf-like" papillae inserting into slit-lilke or cleft-like spaces
Exaggerated intracanalicular pattern - Cellular stroma
- Heterologous differentiation may occur in malignant phyllodes tumor
Liposarcoma Osteosarcoma Chondrosarcoma Rhabdomyosarcoma
Periductal stromal condensation may be seen Frankly sarcomatous stroma may be seen in malignant phyllodes tumor - Heterologous differentiation may occur in malignant phyllodes tumor
