Surgical Pathology Criteria

Juvenile Papillomatosis

Differential Diagnosis

Fibrocystic Disease Juvenile Papillomatosis
Non-circumscribed Circumscribed
Uncommon under age 25 Mean age 20

Pubertal Macromastia Juvenile Papillomatosis
Diffuse Circumscribed
Massive enlargement Mean size 4 cm
Usually bilateral Usually solitary
Predominantly stromal process Prominent cysts

Juvenile Fibroadenoma Juvenile Papillomatosis
Cellular stroma Paucicellular stroma
Canalicular and tubular epithelium Prominent cysts

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