Granulomatous Lobular Mastitis
Differential Diagnosis
- Fungal and acid fast infections must be ruled out by stains and cultures
| Granulomatous Lobular Mastitis | Sarcoidosis |
|---|---|
| Centered on lobules | Widespread distribution |
| Granulomas may not be well formed | Well formed tight granulomas |
| Associated inflammtion may be extensive | Frequently lacks extensive accompanying inflammation (naked granulomas) |
| May have associated fat necrosis and abscess | Necrosis and abscess rare |
| Granulomatous Lobular Mastitis | Mammary Duct Ectasia |
|---|---|
| Centered on lobules | Centered on ducts |
| Granulomatous inflammation | May have giant cells but usually lacks formed granulomas |
| Nearly all cases postpartum | May occur without associated pregnancy |
| Granulomatous Lobular Mastitis | Puerperal Mastitis |
|---|---|
| No infectious organisms | Bacterial infection |
| Mean interval two years from delivery | Recent delivery |

