Surgical Pathology Criteria

Granulomatous Lobular Mastitis

Differential Diagnosis


Granulomatous Lobular Mastitis Sarcoidosis
Centered on lobules Widespread distribution
Granulomas may not be well formed Well formed tight granulomas
Associated inflammtion may be extensive Frequently lacks extensive accompanying inflammation (naked granulomas)
May have associated fat necrosis and abscess Necrosis and abscess rare


Granulomatous Lobular Mastitis Mammary Duct Ectasia
Centered on lobules Centered on ducts
Granulomatous inflammation May have giant cells but usually lacks formed granulomas
Nearly all cases postpartum May occur without associated pregnancy


Granulomatous Lobular Mastitis Puerperal Mastitis
No infectious organisms Bacterial infection
Mean interval two years from delivery Recent delivery

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