Ductal Adenoma of the Breast
Differential Diagnosis
- Nipple adenoma, Radial Scar and Sclerosing adenosis
- Adenomyoepithelioma
- Intraductal papilloma
- Infiltrating ductal carcinoma
Radial Scar, Sclerosing Adenosis, Ductal Adenoma and Nipple Adenoma
- May be considered a spectrum of lesions differing in location and predominant pattern
- All are benign
| Ductal Adenoma | Adenomyoepithelioma |
|---|---|
| Hyalinized stroma | Cellular stroma |
| Circumscribed, encapsulated | Capsule unusual |
| Ductal Adenoma | Intraductal Papilloma |
|---|---|
| Hyperplastic lesion with papillomatosis and/or adenosis | Papillary fronds lacking florid hyperplasia |
| Ductal Adenoma | Infiltrating Ductal Carcinoma |
|---|---|
| Circumscribed, expansile | Infiltrating |
| Cytologically bland | Cytologically atypical |
| Myoepithelial cells present, frequently prominent | No myoepithelial cells |
