Diabetic Mastopathy / Lymphocytic Mastitis
Clinical
- Nearly all reported cases with full constellation of histologic features have occurrred in diabetics
- Most often associated with Type I diabetes
- One report of association with longstanding insulin use rather than type of diabetes (Seidman)
- Occasional cases reported in non-diabetics with some but not all of the diagnostic histologic features
- Significance of such lesions is unclear
- Autoantibodies reported in some cases (Schwartz)
- Generally presents as a fibrous mass or masses
- May be unilateral or bilateral
- One prospective series of diabetics found non-palpable lesions with some but not all of the diagnostic histologic features (Lammie)
- Most patients female
- Virtually all premenopausal
- Rare male cases reported
- May recur
