Apocrine Adenoma of the Breast
Differential Diagnosis
| Sclerosing Adenosis with Apocrine Metaplasia |
Apocrine Adenoma |
| Cellular, sclerotic stroma |
Scant stroma |
| Small glands |
Variable, larger glands |
| Compressed lumens |
Open lumens |
| Apocrine Adenosis |
Apocrine Adenoma |
| Poorly circumscribed |
Circumscribed nodule |
| Variable size and shape of glands |
Uniform round glands |
| Usually associated with adenomyoepithelioma |
No association with adenomyoepithelioma |
| Apocrine Carcinoma |
Apocrine Adenoma |
| Infiltrative pattern |
Circumscribed |
| Large vesicular nuclei with prominent nucleoli |
Small bland nuclei |
| No myoepithelial layer |
Myoepithelial layer present |
