Apocrine Adenoma of the Breast
Definition
- A circumscribed nodule of bland glands with apocrine differentiation
Diagnostic Criteria
- Circumscribed nodule of tightly packed glands
- Glands may have flat or papillary lining
- Scant stroma
- Lumenal cells show apocrine differentiation
- Tall columnar
- Granular eosinophilic cytoplasm
- Bland, basal nuclei
- Mitotic figures described in one report but absent in others
- Apical blebs
- Basal myoepithelial cells present
- Not addressed in publications
- Clearly visible in figures in de Potter 1988
- Cytologically bland
