Urothelial (Transitional Cell) Carcinoma with Chordoid Features
Differential Diagnosis
- Fibromyxoid Nephrogenic Adenoma
In the fibromyxoid areas these may be identical
- Adenocarcinoma
- No glandular differentiation in chordoid urothelial carcinoma
- Yolk sac tumor
- Glypican 3 negative in chordoid urothelial carcinoma
- Mesenchymal lesions with myxoid patterns
- All are essentially ruled out by identification of areas of usual urothelial carcinoma
- Inflammatory myofibroblastic tumor
- Actin positive, p63 negative
- Both are keratin positive
- Extraskeletal myxoid chondrosarcoma
- Myoepithelioma/mixed tumor
- Actin, calponin, GFAP positive
