Primary Effusion Lymphoma
Clinical
- Involves body cavities
- Pleural, pericardial, peritoneal
- Frequently only one cavity involved
- Rare extra-cavitary lymphomas reported with same clinical, viral and immunologic characteristics
- Most frequently seen in HIV positive patients
- Rare cases in HIV negative transplant patients
- Rare cases in elderly HIV negative patients from HHV8 prevalent regions (Mediterranean)
- Rare cases associated with multicentric Castleman disease
- Rare cases in HIV negtive patients with Hepatitis C
- Poor response to therapy
