Lymphomatoid Granulomatosis Variant of Diffuse Large B Cell Lymphoma
Clinical
- Virtually all cases involve lung at some point in disease
- Multiple lung nodules common
- Skin involved in 40-50% of cases
- CNS, kidney, GI tract, head and neck also frequently involved
- Lymphoid organs involved only in late disease
- Most common in forties but wide age range
- Some cases reported associated with HIV or organ transplantation immunosuppression
- Poor prognosis
